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Acarbose attenuates the hypotensive response to sucrose and slows gastric emptying in the elderly

According to the results of the RCT for patients with monogenic obesity ( LEPR or POMC deficiency) and acquired hypothalamic obesity, setmelanotide can reduce body weight and inhibit appetite to a certain extent, and common adverse reactions include injection site reactions, skin hyperpigmentation, nausea, diarrhea, and abdominal pain, with occasional occurrences of sexual adverse reactions, depression, and suicidal ideation [51,52]

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Very low calorie diets (VLCDs), by contrast, produce the worst body composition outcomes

From there, I'll use diagnostic ultrasound to look directly at the tissue