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In 2016, a review commissioned by the UK government concluded that approximately 700,000 people die each year around the globe from antibiotic-resistant infections ( Bacteria in biofilm growth phase are principally responsible for an array of infections within hospital, general health care and community settings ( Pseudomonas aeruginosa virulence factor pyocyanin, and facilitating the growth of human lung epithelial cells ( P

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Conclusion Whilst severe B12 deficiency has a clear clinical picture with characteristic haematological and/or neurological features, establishing mild or borderline deficiency can be problematic as serum levels are maintained at the expense of tissue concentrations, and therefore serum levels of B12 may be in the low normal or borderline range despite a deficiency

The pathophysiological mechanisms that statins attack are identical

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