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doi: 10.15252/embj.2023113491 99 HerhausL

If you are interested in where the field is heading, this paper is one of three or four signposts published in the last six months that point in the same direction: the next decade of metabolic medicine is going to be about precision delivery, multi-mechanism polypharmacology, and genotype-stratified prescribing

In experimental settings, mice fed a high-cholesterol diet exhibited signs of hepatic lipid dysregulation and inflammation, indicative of NAFLD, alongside behaviors resembling depression and anxiety

However, visceral abdominal fat often responds well to treatment due to its high metabolic activity and sensitivity to hormonal changes that occur during weight loss