We first outline the core molecular machinery of ferroptosis, focusing on the interplay between iron homeostasis, lipid peroxidation, the GPX4glutathione axis, and recently identified defense pathways
In obesity treatment, GLP-1 receptor agonists approved for weight management produce clinically meaningful weight loss through multiple mechanisms: reduced appetite and caloric intake via central satiety pathways, delayed gastric emptying, and possible effects on energy expenditure
20% of these adults are obese, or 11m people
Moderate capsaicin-containing kochujang alleviates memory impairment through the gut-brain axis in rats with scopolamine-induced amnesia
However, previous studies have found that DPP-4 can be regulated by inflammatory factors such as signal transducer and activator of transcription 1 (STAT1), hepatocyte nuclear factor-1 (HNF-1), interleukin-12 (IL-12), and tumor necrosis factor- (TNF-) [3335]