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Research indicates that AOD-9604 may act, at least in part, through beta-3 adrenergic receptor (3-AR) signaling a pathway tightly associated with fat oxidation in visceral and brown adipose tissue

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Interestingly, when compared to OA alone, the presence of Ex-4 significantly decreased the expression of SREBP-1, PPAR, CPT1A, ACC, DGAT1, and SCD1 while the expression of ACADL, DGAT2 and FAS remained unaffected (Fig

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