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For example, the ETCM 2.0 database used in our research is human-specific and incomplete, which could introduce certain limitations and biases

After cerebral ischemia/reperfusion in rats, rosmarinic acid was found to increase the phosphorylation of Akt1, decrease the phosphorylation of JK3, and decrease the expression of cleaved caspase-3 to protect hippocampal neurons in the brain (Zhang et al., 2017c)

[6] This enzyme utilizes and stabilizes an acylphosphate intermediate to later perform a favorable nucleophilic attack of glycine

Research on the regulation of the brain-gut axis with the NO pathway (Sikiric et al

It reduces anxious thought patterns without sedation or dependency