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10,193,194 iNAMPT localizes to the cytoplasm, nucleus and mitochondria, and NAMPT has also been found to be upregulated in several solid human tumors, including the colon cancer, 7 glioma 8,9 and breast, 195 prostate, 196 thyroid, 197 and gastric 198 carcinomas
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In erythroleukemia K562 cells, in addition to the above identified NRF2 binding ARE motif, there is also a strong association of active histone codes (such as H3K4Me3, H3K9Ac, H3K27Ac, H3K79Me2) upstream of the transcription start site (Supplementary Fig
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