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GHK-Cu has a plasma half-life of approximately 30 minutes following subcutaneous injection, with serum concentrations dropping below detectable thresholds within 68 hours

Retatrutide carries one side effect not observed with tirzepatide: dysesthesia, a tingling or burning sensation reported in approximately 20.9% of participants receiving the 12 mg dose in Phase 2 trials [3]

Remember: your dose may need to go up

Although this phenomenon has been well described in the literature, we expected it to be less pronounced at the concentration levels used as an excipient, which was not the case

This timeline suggests that generic versions of semaglutide could enter the market sooner, potentially reducing costs for patients