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DOI: 10.1104/pp.109.3.945 68

Amylin, a neuroendocrine anorexigenic polypeptide hormone, with its multi-faceted effects in glucose regulation, weight management and potential CV and neuroprotective functions, represents an attractive new therapeutic target, albeit not without challenges and limitations [29]

In controlled laboratory settings, GLP-1 receptor activation has been associated with: Reductions in alcohol intake Decreased opioid-seeking behaviors Lower rates of binge-like consumption patterns However, findings from animal models do not always translate directly to human outcomes

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