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doi: 10.1007/s00125-007-0692-2 [DOI] [PubMed] [Google Scholar] 58.Holst JJ, Rosenkilde MM

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These medications have been studied extensively in clinical trials and have clear dosing escalation schedules, known side effect profiles, and consistent pharmacokinetics when delivered by injection

Orforglipron's lower manufacturing costs could allow Eli Lilly to price the medication competitively while maintaining higher profit margins, or to pursue an aggressive volume-based pricing strategy that undercuts injectables to capture a larger share of the growing obesity market