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Finally, at the third level of AR regulation, ADT dysregulates the expression of and, less frequently, causes somatic mutations in AR-associated transcriptional regulators that, in a context-dependent manner, control the transcriptional output by AR, and thus ARs effects on CaP cell behavior [30, 40]

One promising avenue combines GLP-1 medications with treatments intended to reduce the loss of skeletal muscle that can accompany rapid weight reduction

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