Diener HC, Rahlfs VW, Danesch U
Preservation of Insulin and Glucose Homeostasis Unlike growth hormone, which can cause insulin resistance and elevated blood glucose (diabetogenic effects), AOD-9604 has demonstrated no negative effects on carbohydrate metabolism
The figure 25.3 % surpasses: Tirzepatide SURMOUNT-1: 22.5 % Semaglutide STEP-1: 14.9 % Retatrutide Phase 2: 24.2 % (comparable, but Phase 3 results for Retatrutide are still lacking) It raises the question whether CagriSema will be the first molecule with an effect truly comparable to bariatric surgery (typically 2530 % reduction)
Every peptide protocol requires careful attention to storage, reconstitution, and administration techniquefactors that matter regardless of dosing frequency
Proper documentation supports consistent use and tracking of the peptide, reducing the risk of errors in experiments