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That story seemed intuitively obvious, and the STEP 9 trial published in NEJM supported it 407 obese patients with knee OA experienced significant pain reduction and improved function with semaglutide 2.4 mg weekly versus placebo

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2011;34(Suppl 2):S2517

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Interview Studying how genomes stay intact July 20, 2026 Patrick OBrien discusses DNA repair, enzyme evolution, scientific publishing and mentorship, reflecting on the curiosity-driven questions that shaped his career and his approach as a JBC associate editor

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