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Zimmerman AW, Jyonouchi H, Comi AM, Connors SL, Milstien S, Varsou A, Heyes MP: Cerebrospinal fluid and serum markers of inflammation in autism

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TPO-Ab positivity, often used as a marker of thyroid autoimmunity, has been associated with elevated pro-inflammatory cytokines, including interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-) (19, 20), which can have systemic effects beyond the thyroid gland (21, 22)

Cell viability was further determined using the CCK-8 assay (Supplementary Fig