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Description

[105] found that overall, TT resulted in decreased Parkinsonian symptoms, measured by the UPDRS, improving from a score of 29 to 22

Nat Commun (2020) 11(1):1251

Therefore, we further explored the underlying mechanism

The binding affinity of GHK for copper(II) is extremely high in the picomolar range for the apparent dissociation constant at physiological pH which means that in the presence of physiological copper, free GHK and copper-bound GHK readily interconvert with the bound form dominating