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469 Importantly, the GLP-1-carotid body pathway may represent a novel therapeutic target for managing cardiovascular metabolism and treating patients with diabetes and hypertension who exhibit heightened sympathetic activity

While GLP-1 agonists don't require specific dietary patterns, emphasizing whole foods, adequate protein (generally 0.8-1.2 g/kg body weight, with higher amounts individualized based on health status), and fiber (25-35 g daily) enhances satiety

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Investigators to bring data on glucose management with oral orforglipron Julio Rosenstock, MD, Francesco Giorgino, MD, PhD, and other panelists will discuss results from the ACHIEVE clinical trials, including ACHIEVE-3, which compared oral semaglutide and orforglipron for use in type 2 diabetes.

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