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doi: 10.1152/physrev.00044.2023 105 Abdel HadiNReyes-CastellanosGCarrierA

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Cell 184 , 62076210 (2021)

Because epithelial cells may also develop copy number alterations (CNA) when expanded ex vivo 56 , we performed whole-genome sequencing, finding only a subpopulation of cells (1729%) with detectable CNA after 8 months in continuous culture, mostly amplifications affecting chromosome 10 (Fig

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