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Glutathione exists in both the thiol-reduced (GSH) form and the disulfide-oxidized (GSSG) form

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In contrast, in the Cagri-AMY 1 R-Gs structure, L119 RAMP1 is likely to clash with a rearranged imidazole side chain of H296 ECL2 that is observed when Cagri is bound to CTR and likely accounts for the different orientation of the linker in the Cagri bound AMY 1 R (Fig

Classification: Research chemical not intended for human consumption