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Systemic SIRT1 insufficiency results in disruption of energy homeostasis and steroid hormone metabolism upon high-fat-diet feeding
Even in animal models, astaxanthin supplementation has shown anti-inflammatory effects in conditions such as atopic dermatitis
Additionally, we also observed a notable downregulation of several key genes involved in macrophage migration and immune response, including Il6 , Ccl2 , Ccl5 , Cxcl2 , Rap1a , and Rap1b 62,63
Normally, the kidney and liver rely heavily on oxidative phosphorylation for energy production as both the liver and the kidney are dense with mitochondria
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