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doi: 10.3389/fnmol.2021.797833 Received 19 October 2021 Accepted 18 November 2021 Published 09 December 2021 Volume 14 - 2021 Edited by Chuang-Rung Chang, National Tsing Hua University, Taiwan Reviewed by Shigeru Yanagi, Gakushuin University, Japan

[81] Healthcare providers should exercise caution when considering melatonin therapy in patients taking immunosuppressive medications and may need to consult with specialists regarding appropriate monitoring strategies