Despite weight regain after retatrutide withdrawal, the anti-tumor benefits of the compound persisted suggesting the effects may not be purely a function of weight loss
Dudek KA, Dion-Albert L, Lebel M, LeClair K, Labrecque S, Tuck E, Ferrer Perez C, Golden SA, Tamminga C, Turecki G, Mechawar N, Russo SJ, Menard C (2020) Molecular adaptations of the blood-brain barrier promote stress resilience vs
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Classification of uremic toxins and their role in kidney failure
They could have off-target negative health effects, and it will be years before we know if they have the same kind of positive effects on long-term heart and kidney health as semaglutide and tirzepatide. But there may also be unanticipated benefits beyond easier use