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Diabetic retinopathy complications may occur in patients with a history of retinopathy

It has been proposed that hyperpigmentation in the epidermal basal layer as well as the presence of dermal melanophages may be due to faulty transfer of melanosomes from melanocytes to keratinocytes, resulting in a lack of melanosomes in keratinocytes in the upper epidermis and pigment incontinence in the dermis

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