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An SDS-PAGE gel can help you answer questions such as: First lets consider a scenario where youre using cell lysate in your pull-down experiment to identify novel interacting proteins
10.1159/000501645 259 SchneiderI.WettsteinA.JenniG.KhneF.HoltforthM.WachsS.et al (2025)
A study of 106 familial melanoma cases (defined as at least two melanoma cases or MPM in the proband) found that 47% of MPM cases and 58% of familial melanoma cases carried this TERT promoter variant.[50,124] POT1 Exome and genome-sequencing in individuals from hereditary melanoma families led to the identification of missense pathogenic variants in POT1 that segregate with disease in numerous studies.[125,126] A POT1 Ser270Asn missense pathogenic variant was found in 5 of 56 unrelated melanoma families from Italy.[125] This variant was not observed in over 2,000 Italian controls
Prog Cardiovasc Dis, 40(3), 265-86
