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The weight loss and blood vessel-widening effects caused by semaglutide can absolutely result in a modest drop in systolic blood pressure for some, says Supriya Rao, MD , a quadruple board-certified physician in internal medicine, gastroenterology, obesity medicine, and lifestyle medicine

6-month: $599 ($99.84/mo)

Its part of a bigger strategy to support long-term health

Previous studies show that mice lacking the GIP-R show more significant arteriosclerosis progression compared to control mice despite having lower body weight, and their blood vessels exhibit increased expression of inflammation-related genes, suggesting that GIP-R stimulation may directly regulate vascular inflammation