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After 12 weeks of taking 2 grams of NR daily, participants had significantly higher NAD+ levels, but their cardiac function did not improve

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Studies on sermorelin and ipamorelin have shown meaningful improvements in lean muscle mass, body fat percentage, and sleep quality (growth hormone is released primarily during deep sleep)

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Luijten 1 , Lotte Haverman 1 1 Amsterdam UMC location University of Amsterdam, Emma Childrens Hospital, Child and Adolescent Psychiatry & Psychosocial Care, Meibergdreef 9, Amsterdam, The Netherlands, 2 UMC Utrecht Brain Center, University Medical Center Utrecht, The Netherlands, 3 De Hoogstraat Rehabilitation, Utrecht, Center of Excellence for Rehabilitation Medicine Utrecht, The Netherlands, 4 CAPHRI, Maastricht University, Maastricht, the Netherlands, 5 Centre of Expertise, Adelante Rehabilitation centre, Valkenburg, the Netherlands, 6 Rehabilitation Science and Physiotherapy, REVAL, Hasselt University, Belgium, Maastricht, Netherlands, 7 Research Group Moving, Growing and Thriving Together, HU University of Applied Sciences, Utrecht, The Netherlands Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :VP4 Aims While self-reported patient-reported outcome measures (PROMs) are preferred, proxies are sometimes necessary