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Potential Side Effects to Know As with any medication, there are some possible side effects to be aware of with semaglutide, including: Nausea - The most common side effect that lessens over time for most people Diarrhea or constipation Abdominal pain Headache Fatigue Dizziness Vomiting - Less common than nausea People with a personal or family history of a type of thyroid cancer called medullary thyroid carcinoma should not take semaglutide due to a possible risk factor

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Melanotan II is discussed online as a melanocortin-pathway peptide associated with increased pigmentation signaling, but responses can vary widely and side effects are commonly reported