3 The Blood Lipids: Cholesterol and Triglycerides Cholesterol Figure 1: Steroid Biosynthesis Pathways 7 Cholesterol is a wax-like steroid molecule that plays a critical role in metabolism
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The resulting cell lysate was filtered through a 0.2-m filter and loaded onto a 5-mL HisTrap HP column (GE Healthcare/Cytiva) equilibrated in wash buffer (50 mM Tris-HCl pH 8.0, 500 mM NaCl, 1 mM TCEP, 25 mM imidazole)
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, Long-term Safety and Efficacy of Achieving Very Low Levels of Low-Density Lipoprotein Cholesterol : A Prespecified Analysis of the IMPROVE-IT Trial, JAMA Cardiol