microdosing glp 1 for menopause GLP-1s for Menopause-Related Weight Gain The Benefits of Micro-Dosing GLP-1

In this trial, 342 men with sildenafil-failure ED were given either intranasal PT-141 (10 mg dose) or placebo on demand over ~48 weeks.The outcomes demonstrated a clear benefit of bremelanotide: About 33.5% of men on bremelanotide achieved a positive clinical response (improved erections sufficient for intercourse) compared to only 8.5% on placebo

However, most modern GLP-1 medications are administered once per week

Int J Cardiol 230:7075

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication

A recent study found that variants in the GLP1R gene, such as rs6923761 GA, can significantly affect the weight loss response to semaglutide [78]