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Important safety considerations include a boxed warning for thyroid C-cell tumors (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2), and pregnancy avoidance (with a 2-month washout period before conception)

These natural antioxidants have gained significant interest due to their potential to prevent CVD, cancer, neurodegenerative disorders, diabetes, and other diseases [270]

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Asiatic acid has evidence of various prerequisites in laboratory animals in diseases such as hypertension, neurodegenerative disorders, diabetes, and cancer