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Curcumin (50 mg/kg), quercetin (50 mg/kg) and a combination of both were orally administered for 14 days before carrageenan injection in rats and compared with the reference nonsteroidal anti-inflammatory drug, indomethacin (10 mg/kg)

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The result provoked cell death, as evidenced by the increased production of cleaved caspase 3 & cleaved poly(ADP-ribose) polymerase 1

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