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Patients with facial NSV(NCT03468855) receiving topical ATI-50002 BID for 24 weeks presented with an improved F-VASI and the Vitiligo Noticeability Scale (VNS) (39)
This non-linear pattern suggests that the body may develop some tolerance to the GI effects at higher maintenance doses, particularly after a proper titration schedule
Additionally, GLP-1 medications slow gastric emptying, which theoretically could affect the absorption of levothyroxine if taken simultaneously
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