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Caution is needed with a history of pancreatitis, gallbladder disease, severe gastrointestinal conditions such as gastroparesis, diabetic retinopathy, or certain other medications, including insulin and sulfonylureas

Similarly, although meal frequency was not explicitly tested in most trials, they say that strategies such as small, frequent meals may help reduce common side effects such as nausea and improve tolerability, especially in the early stages of treatment

Injecting vitamin B12 or taking it sublingually, which means dissolving it under the tongue, allows the vitamin to be delivered directly to the bloodstream

Although these studies cannot prove causation, the consistent findings across large populations, systems, and countries provide compelling early evidence that GLP-1 medications could reduce alcohol and drug use and could play an important role in SUD treatment

New work from the lab