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Immunohistochemistry data demonstrated a 60% reduction in A deposits in the frontal cortex and a 52% reduction in the hippocampus

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The upregulation of mammalian target of rapamycin (mTOR), a master regulator of translation initiation, results in the increased expression of cancer-promoting genes such as eIF4E, a limiting factor for translation initiation in most cancers, including ovarian cancer [79,80]

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Bipolar Disord (2011) 13:41424.10.1111/j.1399-5618.2011.00938.x 133 AdlerCMAdamsJDelBelloMPHollandSKSchmithorstVLevineAet alEvidence of white matter pathology in bipolar disorder adolescents experiencing their first episode of mania: a diffusion tensor imaging study