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I know there are quite a few variables with oral bioavailability, but assuming taken fasted,

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However, the question remained on whether the possible beneficial therapeutic actions of GLP-1 RA in PCOS might depend exclusively on the improvement in body weight and metabolic profile or on direct effects on HPG axis in PCOS

By activating GLP-1 receptors, these drugs enhance glucose-dependent insulin secretion, suppress glucagon release, slow gastric emptying, and influence central appetite signaling

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