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The rest of this guide unpacks each part: which brand is which, what the SUSTAIN trials showed, why the cardiovascular evidence for diabetes patients is a different study from the obesity evidence, dosing, and safety

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One of them, she explained, was whether these drugs helped people lose weight and this weight loss was the key driver behind the heart health improvements, or whether the drugs independently improved heart health

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While this effect has not been conclusively demonstrated in humans, the FDA requires that semaglutides labeling includes a warning about potential thyroid risks