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For instance, in vitro studies using HepG2 cells treated with palmitic acid revealed that the GLP-1RA exendin-4 downregulated the expression of SREBP-1c and FAS, thereby attenuating steatosis (14, 15)

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Frequently Asked Questions (FAQ) What advantages does tirzepatide offer over traditional diabetes treatments

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Key points Amylin is a neuroendocrine peptide hormone, biosynthesized mainly in the pancreatic islet -cells and co-secreted with insulin, that circulates in the blood and controls food intake, glucose homeostasis and energy metabolism