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For example, if youre experiencing nausea, constipation, or other symptoms that are significantly interfering with your quality of life, thats your cue to talk to your healthcare provider

The reality of GLP-1s: Effective but unsustainable From an efficacy standpoint, there is no denying that GLP-1 medications work. Those who can afford, tolerate, and sustain GLP-1 use do lose weight

The net effect is simple: After weight loss, people are hungrier, feel less satisfied after eating and burn fewer calories than expected

That is a 47% greater relative reduction not a marginal statistical difference, but a clinically meaningful one

Food and Drug Administration website.