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Li Y, He Y, Zheng Q, Zhang J, Pan X, Zhang X, et al

Permanent hair reduction is defined as the long-term, stable reduction in the number of hairs re-growing when measured at 6, 9, and 12 months after the completion of a treatment regime, as well as treatment of benign pigmented lesions (sun spots and brown spots), wrinkles, and vascular lesions (such as port-wine stains, hemangiomas, telangiectasias)

Furthermore, it regulated the expression of purinergic receptors (including A2A, A3, P2X4, P2X7, and P2Y1), which are recognized for their significant roles in the inflammatory response associated with DED [77]

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