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TGF- pathway activation occurs with upregulation of TGF- superfamily genes for tissue repair, while simultaneously suppressing pathological TGF-1 secretion in fibrotic conditions

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The strongest direct gastric-emptying numbers in the amylin literature remain those from pramlintide, 3 10 and importing them wholesale onto a structurally modified, kinetically transformed molecule is exactly the kind of extrapolation this article is cautioning against