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Chloroquine suppresses proliferation and invasion and induces apoptosis of osteosarcoma cells associated with inhibition of phosphorylation of STAT3

While the size difference between tripeptides and heptapeptides (e.g., CyRL-QN15) may appear modest in terms of amino acid count, this difference may significantly influence their structural complexity, biological activity, and interaction with cellular targets

We treated HCT116 cells with either DMSO (control) or 50 nM OTS964, isolated chromatin fractions, and digested them with micrococcal nuclease (MNase) 8,59,60

doi: 10.1371/journal.pone.0248691 128

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