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ResearchGate 24:114 Singh A, Rao BM, Deshpande GR et al (2007) A rapid stability-indicating LC method for ziprasidone hydrochloride

Clinical trials show diarrhea typically peaks during dose escalation and often resolves within 48 weeks as the body adapts, though some patients experience persistent symptoms requiring dose adjustment or medication formulation changes

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That framing offers a possible reason why a brain-related signal has shown up across diseases as different as Type 2 diabetes, Parkinsons, and progressive MS

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