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Geography and Competitive Outlook North America has the largest market share due to the high uptake of GLP-1 therapies like Ozempic, Wegovy, strong healthcare infrastructure, as well as many key pharma companies and digital health companies that are primarily located in the North American market

Consistently, regardless of the initial positions of palmitate either located in the membrane as seen in the cryo-EM structure or placed outside of the membrane, our MD simulations found that the -carboxylate spacer stably inserted into the TM1-TM2 cleft and the 16-carbon palmitic chain is deeply buried in the receptor-lipid interface, contributing multiple strong contacts to stabilize the complexes (Supplementary Fig

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Krshnan, L., van de Weijer, M