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Chemosphere 82:16691674 Da Rocha AM, Salomao de Freita DP, Burns M, Vieira JP, de la Torre FR, Monserrat JM (2009) Seasonal and organ variations in antioxidant capacity, detoxifying competence and oxidative damage in freshwater and estuarine fishes from Southern Brazil

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Months 2-3: Cellular signaling continues to accumulate

Compared with unsaturated fatty acids and monounsaturated fatty acids, polyunsaturated fatty acids (PUFAs) are more prone to lipid peroxidation due to unstable carboncarbon double bonds and contribute to ferroptosis[25]