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10.1016/j.cmet.2010.12.008 [DOI] [PMC free article] [PubMed] [Google Scholar] Barrea L., Annunziata G., Muscogiuri G., Laudisio D., Di Somma C., Maisto M

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Yan HH, Jiang J, Pang Y, Achyut BR, Lizardo M, Liang X, et al

Low doses (under 10 mg daily) cause mild glucose elevation, while higher doses (20 mg or more daily) can produce significant spikes, especially in people with existing insulin resistance or prediabetes

It has also been linked to decreased levels of testosterone production due to its impact on insulin sensitivity