Des facteurs, comme une activit physique importante ou certaines pathologies, peuvent acclrer sa diminution
Of note, APOE4 exacerbates mitochondrial dysfunction and oxidative stress within neurons, thereby amplifying neurotoxicity and contributing to neurodegenerative processes (Chen et al., 2021)
HIF stabilisers are emerging as an innovative therapeutic strategy for the treatment of IBD ( In vivo studies with 4-mercapto butyrate confirmed this pattern for systemic HIF stabilisation in mice (Ornelas et al., 2023)
9 (11), e2103672
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