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Phase 2 MASH trial results In overweight or obese participants with metabolic dysfunctionassociated steatohepatitis (MASH), survodutide led to significant histological improvements in 83% of treated patients versus 18% on placebo, based on liver biopsy results

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Typically, transferrin-bound iron predominates, but non-transferrin-bound iron (NTBI) can emerge in plasma during iron overload (Figure 1)