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However, placentas from parental-driven PE (PE1) did not show any changes in mitochondrial protein profiles compared with healthy controls

This effect is probably a consequence of the increased baseline expression of caspase-1 and perhaps other inflammasome-associated factors, such as Gasdermins C2 and C3 that can act as terminal effectors of inflammatory cell lysis 27 , which were observed here in vitro and were previously described in ex vivo proteomics studies of mouse urothelia 8

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82: 810 Udomratn T, Steinberg MH, Campbell Jr GD, et al