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Freeze-thaw cycling can disrupt the copper coordination sphere as well as degrade the peptide backbone, so single-use aliquots in amber or foil-wrapped vessels are preferable to repeated access of one stock

In contrast, upstream migration of tumor cells is regulated by focal adhesions, which polarize at the upstream side of the cell [234]

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The patient should also follow up with his doctor in 3 weeks to evaluate your progress and determine if he needs another injection or other treatments

These qualitative observations provide encouragement during early phases when density changes remain minimal