LRP targeting peptidesAngiopep-2 LRP, including LRP-1 and LRP-2, is a ubiquitous endocytic cell membrane receptor that binds various ligands and controls the permeability of the BBB [96, 125]
Samsung's recently announced purchase of CDMO PolyPeptide Group AG for US$1.8 billion to gain manufacturing capacity is, in the Company's view, a positive indication that Vector is strategically well positioned to take advantage of the rapidly growing demand for peptides
They work through different mechanisms, have very different clinical research behind them, and are suited to somewhat different situations
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The report was uncontrolled, unblinded, not randomized, had no comparator arm, used patient-reported outcomes rather than validated pain instruments, and did not publish dose, effect size, confidence intervals, p-values, or systematically collected adverse events limitations that severely constrain any clinical inference
