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Additionally, AL-fed and DL-fed 3xTg mice of both sexes made more errors during the training phases than CR-fed mice (Fig

Dissociated hippocampal neurons transfected with mRFP-P-actin were stimulated with 10 "12 M Dihexa or 10 ng/ml for 5 days prior to recording mEPSCs

Valdez et al., 2016), although in KO mice lacking kinesin family member 21B (Kif21B), a microtubule-dependent molecular motor that regulates the engulfment of the Rac1-GEF, ELMO1/DOCK complex and enhances Rac1 activity, was found to have unstable LFS-induced LTD without alterations in HFS-induced LTP at CA1 synapses (Morikawa et al., 2018)

Indeed, GCLC has non-canonical functions in sequestering glutamate levels to prevent ferroptosis 51